Vitoss BA2X contains increased levels of bioactive glass compared to Vitoss BA. In-vitro testing showed that it induced two times the deposition of calcium phosphate onto the surface of an implant while retaining the same handling properties.2
Bioactive glass contains three ionic constituents - silicon, sodium, and calcium. Upon implantation, these ionic constituents are released into the surround environment and react with bodily fluids.3-7 This reaction produced the deposition of a thin layer of physiologic calcium phosphate at its surface, favorable for osteoblast attachment.7 This is commonly referred to as a bioactive effect, and may lead to the bonding of new bone to the scaffold.5,8-13 In vitro testing showed cells exposed to Stryker’s proprietary formulation of bioactive glass demonstrated increased cell proliferation, increased collagen elaboration, and increased mineralization compared to cells cultured without exposure to bioactive glass.14
Highly porous beta-tricalcium phosphate (up to 90%)15 containing bioactive glass and resorbs during the natural remodeling process of bone16
Available in Foam Pack forms which can soak and hold various hydration fluids including saline, blood and bone marrow aspirate (BMA)17
The addition of bioactive glass helps create a surface favorable for osteoblast attachment.5,8-13
Note: In-vitro bioactivity testing has not been evaluated in human clinical trials.
Based on BIVIT-WB-9_16136