Studies have shown ClariFix is a simple, clinically proven device that delivers cryotherapy treatment to treat chronic rhinitis.1, 5-8 It allows you to apply focal, controlled freezing to target tissue under direct visualization.4
ClariFix is the only cryotherapy treatment that ablates the posterior nasal nerves and is supported with two years of clinical data.1
ClariFix cryotherapy works by creating second degree nerve damage at the posterior nasal nerves.11-12 This nerve damage results in the loss of axon continuity distal to the freeze, but preservation of the perineurium, endoneurium, and epineurium.10 Cyrosurgery has demonstrated rapid regeneration of mucosal structures and function. Additionally, large blood vessels have shown to be resistant to the freezing and their function is not impaired.15
Treatment target is posterior aspect of middle meatus at point of attachment to lateral wall.
ClariFix device is inserted into nasal cavity under visualization with tip pointed toward lateral wall.
Basal lamella stops cryoprobe from advancing further.
*Most patients begin to see improvement 30 days post treatment.
One system includes: 1 ClariFix cryotherapy device, 2 cryogen canisters and 2 sterile canister caps
Please be aware of contraindications including cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, Raynaud’s disease, open and/or infected wounds or other skin conditions at or near the target tissue. Treat patients with caution who have diabetes, sensitivity to cold, neuropathic disorders, bleeding disorders or impaired peripheral circulation in the area to be treated.4
Most patients see improvement by 30 days post treatment.
In a clinical study, patients reported a significant decrease in runny nose and nasal congestion with four out of five patients reporting long-lasting symptom relief.1, 7-8
Typically, the ClariFix application time is 30-45 seconds per side of the nose.4
Typically, an anesthetic is used to numb the inside of the nose, to ensure patient comfort during the procedure. The ClariFix device is placed in the back of the nose and the cryotherapy is applied. Patients may experience slight pressure, a cooling sensation in the nose and/or around the molars, or some discomfort during and/or after the treatment.
Most patients return to their normal activity that same day. In general, there is minimal downtime and recovery.10
The most common side effects associated with the ClariFix cryotherapy procedure are temporarily increased congestion, transient pain or discomfort, and a headache. Nosebleed is rare, but a potential side effect, and may be increased if the patient has a clotting disorder, uncontrolled high blood pressure, or uses anticoagulants or blood thinners.4
You should discuss with your patient any recommendations to continue taking prescribed rhinitis medications after the procedure.