Cascadia AN 3D
Interbody System
The Cascadia AN 3D Interbody System includes a full range of implant sizes carefully designed to accommodate the vertebral anatomy. This system is used in conjunction with instrumentation that allows for both direct implant insertion and in-situ rotation. Lamellar 3D Titanium Technology incorporates 300-500 um longitudinal channels, which in conjunction with transverse windows can create an interconnected lattice designed to allow for bony integration. [1,2]
Main Features
- Roughened titanium surfaces have been shown to demonstrate increased protein expression in contrast to smooth titanium surfaces [3,4,5]
- Lamellar 3D titanium interbody with approximately 70% porosity [1]
- Reverse hourglass design allows for a large graft volume [1]
- Bulleted nose to ease insertion [1]
- 3-5 μm surface roughness to allow for direct bony ongrowth [1,2]
References:
1. Test Report TR-1220.
2. Loh QL and Choong C. “Three-dimensional scaffolds for tissue-engineering applications: Role of porosity and pore size.” Tissue Engineering Part B 19 (230):1 485-502.
3. Karande TS, Kaufmann JM, and Agrawal CM. “Chapter 3: Functions and Requirements of Synthetic Scaffolds in Tissue Engineering.” Nanotechnology and RegenerativeEngineering: The Scaffold, Second Edition. Ed. CT Laurencin and LS Nair. Boca Raton: CRC Press, 2014. Pages 63-102.
4. Bobyn JD, Pilliar RM, Cameron HU, and Weatherly GC. “The optimum pore size for the fixation of porous-surfaced metal implants by the ingrowth of bone.” ClinicalOrthopaedics and Related Research 150 (1980): 263-270.
5. Karageorgiou V and Kaplan D. “Porosity of 3D biomaterials scaffolds and osteogenesis.” Biomaterials 26 (2005): 5474-5491.
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