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The Global Modular Replacement System is a segmental prosthesis designed for patients requiring extensive reconstruction of the hip joint and/or knee joint, including knee fusions, necessitated by extensive bone loss due to trauma, failed previous prosthesis and/or tumor resection.
The GMRS was developed for reconstruction of large segmental defects for tumors, failed previous arthroplasty or trauma. This system is designed to:
Good or excellent function results in 97% of cases at minimum two-year follow-up, with no difference between sites (distal femur, proximal tibia) or types (primary, revision) of oncologic reconstruction.1
“Low risk of revision and amputation” when using the GMRS prosthesis in patients suffering from bone tumors caused by sarcomas, giant cell tumors, or metastatic bone disease. The authors observed a 74% probability of five-year revision-free survival in the cohort.2
References
1. Pala E, Trovarelli G, Calabrò T, Angelini A, Abati CN, Ruggieri P. Survival of modern knee tumor megaprostheses: failures, functional results, and a comparative statistical analysis. Clin Orthop Relat Res. 2015;473(3):891-899. doi:10.1007/s11999-014-3699-2
2. Yilmaz M, Sørensen MS, Sæbye C, Baad-Hansen T, Petersen MM. Long-term results of the Global Modular Replacement System tumor prosthesis for reconstruction after limb-sparing bone resections in orthopedic oncologic conditions: Results from a national cohort. J Surg Oncol. 2019;120(2):183-192. doi:10.1002/jso.25490
JR-GMRS-SYK-3090749_REV-0