BIO⁴

Viable Bone Matrix

A viable bone matrix containing endogenous bone forming cells (including mesenchymal stem cells, osteoprogenitor cells, and osteoblasts) as well as osteoinductive and angiogenic growth factors

BIO4 Viable Bone Matrix

BIOpossesses all four characteristics involved in bone repair and regeneration: osteoconductive, osteoinductive, osteogenic, and angiogenic.1-3 It is an alternative to autograft that minimizes the potential for harvest site comorbidities. BIO4:

  • Is lot tested for the presence of VEGF (vascular endothelial growth factor)

  • Is lot tested for ≥ 70% cell viability post-thaw

  • Contains ≥ 600,000 cells/cc (endogenous bone forming cells including mesenchymal stem cells)

  • Is ready to use out of the package; no decanting is required, and thaws in 15 minutes

  • Has differentiated handling compared to competition

  • Is non-immunogenic

  • Is available in 1, 2.5, 5 and 10cc sizes