Tritanium In-Growth Technology1

Stryker’s proprietary Tritanium In-Growth Technology, used to build the Tritanium PL Cages, was designed for bone in-growth and biological fixation. Inspired by the microstructure of cancellous bone, and enabled by Stryker’s patent-protected 3D Additive Manufacturing process, this technology is deliberately designed for fusion.


Tritanium PL Cage video


Tritanium In-Growth Technology with porcine bone marrow aspirate*



This test demonstrated that a cube built with Tritanium material was able to wick fluid into the porous structure under specified conditions15


It also absorbed and held fluid inside the porous structure15


*This experiment was performed using heparinized porcine bone marrow aspirate. No correlation to human clinical outcomes has been demonstrated or established

Material characteristics for bone in-growth and biological fixation1

  • Strong, stiff and biocompatible material2

    Made from titanium alloy

  • Highly porous material4,5,6

    Porosity > 46%

    Average pore diameter > 300μm

    Mean porosity: 60%

    Pore diameter range: 100-700μm

    Mean pore diameter: 438μm

  • Interconnected porosity7

    Porosity on superior and inferior surfaces and within internal walls

  • Roughened surface2,3

    Coefficient of friction = .92

  • Porous architecture reflective of bone composition5

    Tritanium material consists of random interconnected architecture with rugged, irregular pore sizes and shapes that are designed to mimic cancellous bone

  • Manufacturing process capable of reproducible randomization

    Utilizes proprietary Laser Rapid Manufacturing technique to produce completely randomized yet reproducible porous structure

Note: Tritanium is a novel highly porous titanium material designed for bone in-growth and biological fixation. These claims are exclusively associated with Tritanium Technology, used to build the Tritanium PL Cage.

Designed for in-growth

Tritanium technology has been designed for bone in-growth and biological fixation.

  • Cancellous bone characteristics5

    Average pore diameter of cancellous bone = 1 mm

    Average porosity of cancellous bone = 50–90%

  • Tritanium material characteristics9

    Randomized pore sizing designed to mimic cancellous bone - Pore size range: 100-700 μm - Mean pore size: 438 μm

    Interconnected pore structure from endplate to endplate - Mean porosity: 60%

Tritanium pre-clinical research

Sagittal view. Correlation to human clinical outcomes has not been demonstrated or established.

Tritanium PL Cage design

Stryker’s Tritanium PL Cage is a hollow, rectangular implant that consists of a unique configuration of both solid and porous structures, which are simultaneously built using 3D Additive Manufacturing applying Stryker’s proprietary Tritanium In-Growth Technology.

Developed to minimize subsidence10

The Tritanium PL Cage demonstrated better resistance to subsidence than other commercially available posterior lumbar interbody cages constructed out of different materials, including those with a larger footprint.10

  • Porous Tritanium has an elastic modulus that falls between cancellous and cortical bone10

  • Large central graft and lateral windows help to reduce the overall stiffness of the cage10 and allow room for bone graft to be packed inside the cage

  • Teeth are designed to increase the surface area of the device in contact with bone in order to help normalize load transmission and minimize subsidence10

Created to allow imaging

With large lateral windows, Tritanium PL allows visualization on CT and X-ray.

Images taken from a cadaveric study 14

Engineered for stability11,12

The precisely angled teeth of the Tritanium PL Cage are designed to allow bidirectional stability, with an expulsion force that was shown to be 22% greater than the insertion force.11

  • Teeth with a smooth leading edge aid movement across the vertebral endplates

  • High coefficient of friction for initial stability12

Empowered by expertise

Stryker’s Tritanium technology has been utilized clinically for more than 10 years with more than 300,000 orthopaedic devices implanted.13

Stryker’s high resolution 3D Additive Manufacturing process, which incorporates hundreds of quality checks per batch, enables Tritanium PL Cages to be designed and built with pinpoint precision.13

Tritanium PL Cage technical data9

  • Titanium alloy
  • Mean 60%
  • Mean 438 μm
  • 100-700 μm
  • Full, endplate to endplate
  • Lengths23 and 28 and 32mm
  • Widths9 and 11 mm
  • Lordosis0, 6 and 12°
  • Heights7–14 mm

Built with laser precision,layer by layer13

News & events

Keep up with Stryker news to stay informed and up to date with the latest in medical technology.

Recent news

  • AAOS 2017

    New Tritanium PL Cage sizes debut at AAOS...

    More

  • Animal Study

    Pre-Clinical study presented at NASS...


    More

  • NASS 2016

    Experience virtual reality at NASS 2016...


    More

  • Tritanium posterior lumbar cage debuts

    Stryker's Spine division will introduce the Tritanium Posterior Lumbar (PL) Cage... More

  • Stryker receives FDA clearance for Tritanium

    Advanced 3D additive manufacturing technology used to create proprietary tritanium... More

Upcoming events

Press kit

  • Backgrounder

    Advances in 3D printing pioneered by Stryker have led to the development of Tritanium... More

  • Disc disease facts

    Stryker is one of the world's leading medical technology companies and... More

  • Tritanium facts

    Patients with degenerative disc disease often experience back pain, which typically is... More

Graphics library

  • PL Cage

    Product image of the PL Cage in TIF format. Download


For information contact:
Jodie Morrow, Stryker
Barbara Sullivan, Sullivan & Associates

Inspired by biology Enabled by technology Built to fuse

Request more information
References
  1. 1.  Tritanium technology claim support memo PROJ 43909
  2. 2.  Oldani C, Dominguez A. Titanium as a Biomaterial for Implants. Recent Advances in Arthroplasty. Dr. Samo Fokter (Ed.). ISBN: 978-953-307-990-5. 2012. InTech.
  3. 3.  Deligianni DD, Katsala N, Ladas S et al. Effect of surface roughness of the titanium alloy Ti-6Al-4V on human bone marrow cell response and on protein adsorption. Biomaterials. 2001;22(11):1241–51.
  4. 4.  Kujala, S. et al (2003): “Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel–titanium bone graft substitute”, Biomaterials, 24(25), November 2003, Pages 4691-4697.
  5. 5.  Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005 Sep;26(27):5474-91.
  6. 6.  Bobyn JD, Pilliar RM, Cameron HU, Weatherly GC. (1980) The optimum pore size for the fixation of porous-surfaced metal implants by the ingrowth of bone. Clinical Orthopaedics and Related Research, 150, 263-270.
  1. 7.  Simon JL, Roy TD, Parsons JR, Rekow ED, Thompson VP, Kemnitzer J, et al. Engineered cellular response to scaffold architecture in a rabbit trephine defect. J Biomed Mater Res A 2003;66(2):275–82.
  2. 8.  Pre-clinical study final report SRL 15-02 / Stryker -02-15
  3. 9.  DHF 42351
  4. 10. Subsidence memo PROJ 42624
  5. 11. Insertion and expulsion forces memo PROJ 42623
  6. 12. Coefficient of friction memo PROJ 44960
  7. 13. Data on file, Stryker’s Spine division
  8. 14. Tritanium PL Cage cadaveric image folder | Stryker document #0000047030
  9. 15. RD0000050927

USA and Canada Indications
The Tritanium PL cage is an intervertebral body fusion device indicated for use with autograft and/or allogenic bone graft comprised of cancellous and/or corticocancellous bone graft when used as an adjunct to fusion in patients with degenerative disc disease (DDD) at one level or two contiguous levels from L2 to S1. DDD is defined as back pain of discogenic origin with degeneration of the disc confirmed by history and radiographic studies. The DDD patients may also have up to Grade I spondylolisthesis at the involved level(s). These patients should be skeletally mature and have six months of non-operative therapy. Additionally, the Tritanium PL cage can be used as an adjunct to fusion in patients diagnosed with degenerative scoliosis. The Tritanium PL cage is to be implanted via a posterior approach. The Tritanium PL cage is intended to be used with supplemental spinal fixation systems that have been cleared for use in the lumbosacral spine.

Indications Outside USA and Canada
The Tritanium PL Cage is an intervertebral body fusion device indicated for the treatment of spondylolisthesis, degenerative spine disorders and discal and vertebral instability, and may also be used in cases of spine revision surgery. Packing bone graft material within the implant is recommended. The Tritanium PL Cage is to be implanted via a posterior approach. The Tritanium PL Cage is intended for use with supplemental fixation.

This website is intended for physicians only. It is not intended for patients. If you are a patient, you should not rely on the information on this website and should speak to your doctor about whether spinal fusion surgery is right for you.

A surgeon must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. Stryker does not dispense medical advice and recommends that surgeons be trained in the use of any particular product before using it in surgery.

The information presented is intended to demonstrate the breadth of Stryker product offerings. A surgeon must always refer to the package insert, product label and/or instructions for use before using any Stryker product. The products depicted are CE marked according to the Medical Device Directive 93/42/EEC. Products may not be available in all markets because product availability is subject to the regulatory and/or medical practices in individual markets. Please contact your Stryker representative if you have questions about the availability of Stryker products in your area.

Stryker Corporation or its divisions or other corporate affiliated entities own, use or have applied for the following trademarks or service marks: Built to fuse, Stryker, Tritanium. All other trademarks are trademarks of their respective owners or holders.

TRITA-WB-2_13697

Copyright © 2017 Stryker